The true toll of that festive tipple: Hour by hour, how excess plays havoc with your mind and body

The true toll of that festive tipple: Hour by hour, how excess plays havoc with your mind and body Why is that first festive drink so cheering — and why can’t you stop there And what exactly makes you feel so dreadful the morning after As the Christmas party season gets into full swing, we ask the experts what happens to the body during and after drinking alcohol — and how you can minimise its effects. After just one drink, alcohol boosts the levels of four key brain chemicals – dopamine, serotonin, naturally occurring opioids and gamma-aminobutyric acid 8pm: THE HAPPIEST YOU’LL BE ALL NIGHT When that first drink reaches your stomach, the alcohol enters your bloodstream, where it makes a beeline straight for your brain’s pleasure centres.